GAO As of 2021, the Departments of Commerce, Energy, and Defense have invested nearly $2 billion in America Makes, NextFlex, and 14 other innovation groups in the Manufacturing USA network. These groups include: 1. Advanced Functional Fabrics of America (AFFOA) Website: https://affoa.org Location: Cambridge, MA AFFOA is advancing the ability to manufacture functional fiber and fabric technology with applications such as body-worn sensing and communications for both national security and commercial purposes. 2. American Institute for Manufacturing Integrated Photonics (AIM Photonics) Website: https://www.aimphotonics.com Location: Albany, NY AIM Photonics is developing manufacturing technology for photonic integrated circuits, circuits that use light for applications that traditionally function with electronics. 3. National Additive Manufacturing Innovation Institute (America Makes) Website: https://www.americamakes.us Location: Youngstown, OH America Makes is advancing additive manufacturing or 3D printing, with applications ranging from automotive production to medical equipment production such as personalized joint implants. 4. Advanced Robotics for Manufacturing (ARM) Institute https://arminstitute.org Location: Pittsburgh, PA The ARM Institute is strengthening U.S. manufacturing through innovation in robotics and artificial intelligence (AI), and by preparing the workforce to work alongside these technologies. 5. BioFabUSA Website: https://www.armiusa.org Location: Manchester, NH A program of the Advanced Regenerative Manufacturing Institute, BioFabUSA is focused on accelerating development of critical biotechnologies for cell, tissue, and organ-based products and building a domestic ecosystem for advanced biomanufacturing that supports national security, health resistance, and economic growth. 6. Bioindustrial Manufacturing and Design Ecosystem (BioMADE) Website: https://www.biomade.org Location: St. Paul, MN BioMADE aims to enable domestic bioindustrial manufacturing at all scales, develop technologies to enhance U.S. bioindustrial competitiveness, de-risk investment in relevant infrastructure, and expand the biomanufacturing workforce to realize the economic promise of industrial biotechnology. 7. Collaborative Ecosystems Smart Manufacturing Innovation Institute (CESMII) Website: https://www.cesmii.org Location: Los Angeles, CA CESMII seeks to develop and deploy advanced sensors, controls, platforms, and modeling technologies to improve energy efficiency, productivity, and competitiveness of U.S. manufacturers. 8. Cybersecurity Manufacturing Innovation Institute (CyManII) Website: https://cymanii.org Location: San Antonio, TX CyManII focuses on the research, development, and implementation of manufacturing cybersecurity that enables energy-efficient manufacturing and secures manufacturing operations and supply chains. 9. Electrified Processes for Industrial eXCellence (EPIXC) Website: https://epixc.org Location: Tempe, AZ EPIXC focuses on developing and scaling innovative hybrid electric heating technologies to improve the affordability, flexibility, and energy efficiency of industrial process heating. 10. Institute for Advanced Composites Manufacturing Innovation (IACMI) Website: https://www.iacmi.org Location: Knoxville, TN IACMI aims to accelerate development and adoption of cutting-edge technologies for advanced composites to strengthen U.S. manufacturing and national defense. 11. National Advanced Materials and Manufacturing Innovation Institute (LIFT) Website: https://lift.technology Location: Detroit, MI LIFT promotes the development and deployment of advanced lightweight materials, manufacturing processes, and systems engineering to enhance U.S. manufacturing competitiveness and economic and national security. 12. Manufacturing times Digital (MxD) Website: https://www.mxdusa.org Location: Chicago, IL MxD works to strengthen the U.S. industrial base by solving critical manufacturing challenges, developing the workforce, and advancing digital adoption by modernizing supply chains and ensuring safe and secure cybersecurity practices. 13. America’s Flexible Hybrid Electronics Manufacturing Institute (NextFlex) Website: https://www.nextflex.us Location: San Jose, CA NextFlex strives to enhance, improve, and drive the manufacturing maturity of flexible hybrid electronics across the United States. 14. National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL) https://www.niimbl.org Location: Newark, DE NIIMBL seeks to accelerate the translation of new discoveries in biotechnology into safe, effective, and affordable treatments for patients, while promoting the growth and competitiveness of the U.S. biopharmaceutical industry. 15. PowerAmerica Website: https://poweramericainstitute.org Location: Raleigh, NC PowerAmerica focuses on accelerating commercialization of new wide-bandgap power electronic devices and systems to improve performance and strengthen the U.S. manufacturing supply chain for a wide range of applications. 16. Rapid Advancement in Process Intensification Deployment (RAPID) Institute Website: https://rapid.aiche.org Location: New York, NY RAPID focuses on advancing chemical process intensification technologies to improve productivity and efficiency, cut operating costs, and reduce waste. 17. Reducing EMbodied-energy And Decreasing Emissions (REMADE) Institute Website: https://remadeinstitute.org Location: Rochester, NY REMADE focuses on driving down the cost of technologies essential to reuse, recycle, and remanufacture materials such as metals, fibers, polymers and electronic waste. GAO